NOT KNOWN DETAILS ABOUT LDN-27219 SIDE EFFECTS

EC dysfunction, characterized by blunted relaxations in reaction to acetylcholine and reduced NO bioavailability, was located in the aortas of male HAS-two mice, whilst it was unaltered in the aortas of female HAS-2 mice. Superoxide concentrations amplified and extracellular superoxide dismutase (ecSOD) expression diminished during the aortas of ma